Comparative Assessment of Contact Osteogenesis at the Titanium Implant-Bone Junction in Male Rabbits with Dissimilar Femoral Defects

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Duma, V.; Gal, A. F.; Rus, V.; Matei-Latiu, Maria-Catalina; Ratiu, C.; Alexandru, B. C. & Latiu, C.; Martonos, C. & Oana, L. I.


Traumatized bone tissue has the capacity to repair itself so that it eventually regains its almost original form, even in the case of artificially inserted implants. The process that stays at the base of the regeneration is represented by osteogenesis or remote osteogenesis. The major difference between the two types of bone formation is the location of the cement line, which is located on the surface of the implant for contact osteogenesis and on the surface of the bone defect for remote osteogenesis. The aim of the present study was to assess the contact osteogenesis in the case of inserted titanium screws in holes with diameters of 1.8 mm and 1 mm respectively. The obtained results show, in the case of the groove with 1.8 mm that the newly proliferated bone represents 73.85 % of the total area, while in the case of the groove with 1 mm in diameter the value of the newly proliferated bone is 26.15 %. In conclusion, the insertion of titanium screws by self-tapping into the hole smaller than the core of the screw is accompanied by bone proliferation by contact osteogenesis much more modest than in the case of insertion into the hole larger than the core of the screw.

KEY WORDS: Titanium implant; Osteogenesis; Bone repair.

How to cite this article

DUMA, V.; GAL, A. F.; RUS, V.; MATEI-LATIU, M. C.; RATIU, C.; ALEXANDRU, B. C. & LATIU, C.; MARTONOS, C. & OANA, L. I. Comparative assessment of contact osteogenesis at the titanium implant-bone junction in male rabbits with dissimilar femoral defects. Int. J. Morphol., 41(5):1317-1322, 2023.