Thermal Injury Protocol to Study Healing, With and Without Infection, in Guinea Pig (Cavia porcellus) Model

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Jessica Salvo; Carolina Schencke; Mónica Pávez; Carlos Veuthey & Mariano del Sol


Experimental healing studies in humans are complex and difficult to replicate in vitro. Hence, animal models are needed to study the different stages involved. The guinea pig (Cavia porcellus) is a model close to human physiology, including the lack of vitamin C synthesis, a precursor of collagen fibers for healing. The thermal injury in this animal makes it possible to study all the stages of healing, taking few days to show tissue repair in the processes with and without localized infection. The aim of this work was to systematize an experimental guinea pig (Cavia porcellus) animal model protocol for studies on healing with and without localized infection.

KEY WORDS: Animal model; Cavia porcellus; Wound healing.

How to cite this article

SALVO, J.; SCHENCKE, C.; PÁVEZ, M.; VEUTHEY, C. & DEL SOL, M. Thermal injury protocol to study healing, with and without infection, in guinea pig (Cavia porcellus) model. Int. J. Morphol., 41(4):1053-1057, 2023.