Biomarkers and image markers of Alzheimer's disease

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Pardi, P.C.; Santos, G.A.A.; Silva Gois, J.C.; Braz Jr., R.G. & Olave, E.


This article presents a bibliographical analysis of markers and biomarkers of Alzheimer's disease (AD). The methodologies used were the imaging markers (Magnetic Resonance and Positron Emission Tomography) and biomarkers of the BA42 protein, Tau protein and Apoliprotein E (ALPE). Thus, decreased levels of BA42, increased Tau, ALPE polymorphisms, and alterations in imaging markers are important as risk factors for the development of AD. A review of the literature is made regarding the clinical findings of this disease.

KEY WORDS: Apolipoprotein; Tau Protein; Biomarkers.

How to cite this article

PARDI, P. C.; SANTOS, G. A. A.; SILVA GOIS, J. C.; BRAZ, Jr. R. G. & OLAVE, E. Biomarkers and image markers of Alzheimer's disease. Int. J. Morphol., 35(3):889-894, 2017.