NAFLD and High Fructose Intake. A Review of Literature

Tweet about this on TwitterShare on FacebookEmail this to someoneShare on Google+

Pamela Carvallo; Eugenia Carvallo; Sandra Barbosa-da-Silva; Carlos Alberto Mandarim-de-Lacerda & Mariano del Sol


One of the most commonly used sweeteners is fructose. Fructose is directly metabolized in the liver and can be converted into glucose, later stored as glycogen constituting a source of energy for the hepatocytes. All excess fructose is converted into lipids by exerting a toxic effect on the liver, similar to that produced by excess of alcohol, and can cause nonalcoholic fatty liver (NAFLD). The aim of this review is to gather recent findings regarding the effect of fructose intake at high concentrations and its relationship with NAFLD.

KEY WORDS: Hígado graso no alcohólico; esteatohepatitis no alcohólica; fibrosis hepática; Fructosa.

How to cite this article

CARVALLO, P.; CARVALLO, E.; BARBOSA-DA-SILVA, S.; MANDARIM-DE-LACERDA, C. A. & DEL SOL, M. NAFLD and high fructose intake. A Review of Literature. Int. J. Morphol., 35(2):676-683, 2017.