Plastination is a conservation technique which allows anatomical pieces to be preserved, dry and odor-free, for an indefinite period. In particular, plastination of sections of tissue with epoxy resin allows very thin slices to be made of various regions of the anatomy, permitting close viewing of anatomical structures which are difficult to access by dissection or cadaver exploration. The objective of this work is to present a plastination technique developed in our laboratory for tissue sections using commercial epoxy resin, as an alternative to the existing classic plastination techniques. The technique was applied to a human knee, obtaining 5 mm thick sections which were compared with computerized tomography images. The development of an alternative sheet plastination technique using epoxy resin allows the preservation of anatomical regions which are difficult to study, with the possibility of comparing the sections with imaging studies. In this way anatomy can be usefully combined with clinical experience, allowing students to gain more significant knowledge of anatomy. The technique would also ensure provision of anatomical samples for research in the area of morphological science.