Effects of Formaldehyde and Vimentin Expression in Rat Skin

DOI : http://dx.doi.org/10.4067/S0717-95022013000300011
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Sevgi Kalkanli; Nevin Kalkanli; Engin Deveci; Tuba Dal & Özlem Baran

Summary

The Wistar rats ( 9 weeks old, 180–200 g body weight) used in these trials were divided into two groups of 16 animals each (Control group and Experimental group). 100x65x100 in the sizes of the experimental group were taken into a glass vase. During the time period of 8 weeks, 5 days a week with 8 hours the inhalation of 10 ppm formaldehyde was made. Skin was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine, Trichrome-Masson and observed under light microscope. In this study, histopathological and immunohistochemical techniques due to the impact of the changes in formaldehyde and examined the distribution of vimentin.

KEY WORDS: Formaldehyde; Skin; Vimentin.

How to cite this article

KALKANLI, S.; KALKANLI, N.; DEVECI, E.; DAL, T. & BARAN, O. Effects of formaldehyde and vimentin expression in rat skin. Int. J. Morphol., 31(3):845-848, 2013.