Effect of Sesame-Supplemented Diet on Prostate and Seminal Vesicle Histology of Adult Rat

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Javad Amini Mahabadi; Hassan Hassani Bafrani & Hossein Nikzad


Infertility is a great concern among the people of reproductive age. The use of natural products obtained from traditional herbs is appealing. Studies show that antioxidants are important in improving male infertility. Thirty adult male rats were randomly divided into two regimen and control groups. The regimen group received diet containing 30 % sesame seed, while the control group received standard diet for 12 weeks. Histology of prostate and seminal vesicle were evaluated and serum levels of FSH, LH and testosterone concentrations were assessed as well. The results showed that, the diameter of peripheral epithelium and the volume density of the prostate epithelium increased but the volume density of the prostate stroma was decreased significantly in the regimen group compared to the control group. Central epithelium diameter and the volume density of the prostate lumen did not change significantly between two groups. In seminal vesicle, volume density of fibromascular and lumen decreased significantly in regimen group compared to control group. FSH andTestosterone level did not change while LH concentration increased significantly in the regimen group compared to the control group (P<0.03). This study shows that the sesame seed might improve male rat reproductive systems by histopathological changes in prostate and seminal vesicle.

KEY WORDS: Prostate; Seminal vesicle; Sesame seed; Sperm; Hormone.

How to cite this article

MAHABADI, J. A.; BAFRANI, H. H. & NIKZAD, H. Effect of sesame-supplemented diet on prostate and seminal vesicle histology of adult rat. Int. J. Morphol., 34(2):604-609, 2016.