Does the use of Testosterone Enanthate as a Form of Doping in Sports Cause Early Closure of Epiphyseal in Bones?

DOI : 10.4067/S0717-95022015000400001
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Sefa Lok

Summary

The purpose of this research is to investigate the morphometric effects of short term usage of testosterone enanthate among the anabolic androgenic steroids used as doping by athletes on humerus bones of male rats. 30 rats (35 days) were utilized in this research. The rats were divided into three equal groups. For the experimental group (n= 10), testosterone enanthate at 10 mg/kg dose in 100 µl peanut oil diluents, for the peanut oil group (n= 10), peanut oil of testosterone enanthate' diluent (100 µl) was executed intraperitoneally 5 days in a week for 3 weeks. The control group (n= 10) was nourished without any practice for 3 weeks. All rats were euthanized end of the research. Humerus bones were exposed by the dissection of rats' front extremite bones and measurements and the averages were taken. When the length of rats' humerus bones were analyzed, the growth of humerus bones of rats testosterone enanthate applied in the experimental group stopped significantly and the difference was significant (p<0.05). It was observed that among anabolic androgenic steroids, testosterone enathate's usage on male rats in puberty period caused early epiphyseal closure and stopped the growth of humerus bones significantly.

KEY WORDS: Sport; Doping; Testosterone enanthate; Bone; Humerus; Morphometry.

How to cite this article

LOK, S. Does the Use of Testosterone Enanthate as a Form of Doping in Sports Cause Early Closure of Epiphyseal in Bones? Int. J. Morphol., 33(4):1201-1204, 2015.