4NQO Carcinogenesis: A Model of Oral Squamous Cell Carcinoma

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César Andrés Rivera Martínez


The experimental oral carcinogenesis induced by the chemical 4-nitroquinoline 1-oxide (4NQO) is one of the most frequent in the study of squamous cell carcinoma of the oral cavity (CCEC). The clear advantage is that the model is very similar to the physiological process of malignancy. The model has clear benefits by and is suitable for applications in therapeutic research.

KEY WORDS: 4NQO; Experimental carcinogenesis; Oral squamous cell carcinoma; Tongue.

How to cite this article

RIVERA, M. C. A. 4NQO carcinogenesis: a model of oral squamous cell carcinoma. Int. J. Morphol., 30(1):309-314, 2012.