Gene polymorphism ACTN3 and ACE in selected gymnasts in Brazil and Japan.

DOI : http://dx.doi.org/10.4067/S0717-95022015000100041
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Andrea Ferreira João; Alexis Caniuqueo Vargas; Claudio Hernández Mosqueira; Sandro Fernandes da Silva; Mikel Izquierdo; Hector Silva Mella; Rodrigo Ramirez-Campillo & José Fernandes Filho

Summary

In the field of competitive sport, genetics has gained a fundamental role in the study of sport performance. The aim of this study was to analyze the prevalence of polymorphisms R577X and insertion/deletion (I/D), occurring in a-actinin-3 (ACTN3) and angiotensin converting enzyme (ACE) genes, respectively, in Brazilian and Japanese gymnasts. A suitable non-probabilistic sample of 73 gymnasts (14 from Japan) was recruited and signed an informed consent. To measure ACTN3 and ECA saliva samples were obtained by means of real time polymerase chain reaction (iQ5 Thermal Cycler, BioRad). A high prevalence of RX ACTN3 genotype, R allele, ACE I/D genotype, and D allele were observed in Brazilian and Japanese gymnasts. In conclusion a high prevalence of RX ACTN3 genotype, R allele and ACE I/D genotype would allow a genetic advantage regarding muscle strength and power, possibly facilitating competitive success in gymnastics.

KEY WORDS: Polymorphism; Angiotensin converting enzyme; a-actinin-3; Sport performance.

How to cite this article

JOÃO, A. F.; CANIUQUEO, V. A; HERNÁNDEZ, M. C.; DA SILVA, S. F.; IZQUIERDO, M.; SILVA, M. H.; RAMIREZ- CAMPILLO, R. & FERNANDES FILHO, J. Gene polymorphism ACTN3 and ACE in selected gymnasts in Brazil and Japan. Int. J. Morphol., 33(1):262-266, 2015.