Expression of VEGF and CD68 in the placenta of gestational diabetic mothers (Immunohistochemistry and ultrastructural study).

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Yavuz, D.; Balsak, D.; Ekinci, C.; Tahaoglu, A. E.; Togrul, C.; Görük, N.; Aktas, A. & Karaman, E.

Summary

Placental angiogenesis, is essential for embryonic and fetal development. In this study, 18 gestational diabetes mellitus and 22 control pregnancies were included. Gestational diabetes mellitus (GDM) groups compared to the control group significantly higher values were detected (p<0.01). The following histological results were assessed; villous immaturity, chorangiosis, presence of, sncytial knots,mononuclear cell infiltration ischemia and fibrinoid necrosis. To evaluate and compare the placental histology of normal and GDM pregnancies. placentas of pregnant women with gestational diabetes also in terms of angiogenesis and macrophages and ultratructural revealed by examining the possible relationship between fetal complications were investigated.

KEY WORDS: Gestational Diabetes (GDM); VEGF; CD68; Ultrastructure.

How to cite this article

YAVUZ, D.; BALSAK, D.; EKINCI, C.; TAHAOGLU, A. E; TOGRUL, C.; GÖRÜK, N.; AKTAS, A. & KARAMAN, E. Expression of VEGF and CD68 in the placenta of gestational diabetic mothers (Immunohistochemistry and ultrastructural study). Int. J. Morphol., 33(2):522-526, 2015.