Frequency of Genetic Polymorphism ACTN3 R577X and ACE I/D in Blind Athletes of 5-a-Side Football

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Glauber Lameira Oliveira; Talita Adão Perini Oliveira; Ramon Pereira Souza; Soraia Izabel Corrêa Cabral; João Rafael Valentim-Silva; José Irineu Gorla & José Fernandes Filho


The aim of this study was to describe the genotypic and allele frequency of ACTN3 R577X and ACE I/D in blind athletes of 5-a-side football performance. A descriptive methodology was included with a sample of 63 blind male athletes (28.0 ±5.8 years) of football teams with a 5-a-side performance rating. The polymorphism was determined by means by of real-time Polymerase Chain Reaction (rt-PCR). Statistics were descriptive based on the measures of frequency of genotypes and alleles. The genotypic frequency of ACTN3 by the athletes presented the following distribution: 28.6 % with RR genotype, 54 % with RX and 17.4 % XX and allele frequency of 55.6 % for the R allele and 44.4 % for the X allele. As for ACE I/D, the genotype frequency was 63.5 % for genotype ID, 22.2 % for DD and 14.3 % for II. The allele frequency showed a predominance of the D allele with 53.9 %. The study found for ACTN3 R577X and ACE I/ D of blind athletes of 5-a-side football, a predominance of genotypes and alleles representative of strength and speed modalities.KEY WORDS: Visual impairment; Paralympic; Polymorphism.

How to cite this article

OLIVEIRA, G. L.; OLIVEIRA, T. A. P.; SOUZA, R. P.; CABRAL, S. I. C.; VALENTIM-SILVA, J. R.; GORLA, J. I. & FERNANDES FILHO, J. Frequency of Genetic Polymorphism ACTN3 R577X and ACE I/D in Blind Athletes of 5-a-side football. Int. J. Morphol., 38(5):1336-1340, 2020.